Alleviating the oxidative stress in Japanese quails fed L- carnitine and creatine monohydrate through impacts on productive performance, ileal microflora, digestibility and redox system

This study was aimed to investigate the effects of L-carnitine (Car), creatine monohydrate (CrM) and their combination (CarCrM) as dietary antioxidants materials on productive performance, digestibility, ileal eubiosis, blood chemistry redox system stressed quails challenged by lead acetate (LA) in drinking water. In total, 600 were assigned into 5 treatments with 4 replications each 30 chicks per replication from 1 until 42 days old. The involved control (T1), treatment (adding 2.5 ppm LA water only; T2) adding 500 mg/kg Car+LA (T3), CrM+LA (T4) CarCrM (250 Car plus 250 CrM)+LA (T5). A completely randomized design followed analyze influences variables. comparison T2, results showed that T5 T4 had equivalent positive influence T3 increase (p≤0.05) body weight, feed intake, survivability, carcass yield digestibility accompanied lactic acid bacteria reduced total coliform, E.coli ileum. Also, increased levels glutathione peroxidase, superoxide dismutase, catalase serum ferric-reducing ability plasma obtained T4. Moreover, achieved low values efficiency lipid hydroperoxide, malondialdehyde, cortisol, aspartate transaminase, alanine aminotransferase, alkaline phosphatase,gamma-glutamyl transferase, kinase creatinine. confirm or CrM mitigated stress reinforced antioxidant pool which reflected supported physiological aspects birds. Dietary seemed less powerful effect than but without negative compared treatment.